Contract Manufacturing

Large-scale and multifunctional reactors at our manufacturing site have enabled us to become a one-stop manufacturing location for our customers’ high-volume intermediate and APIs manufacturing needs. Our ability to develop and validate custom intermediates and APIs, along with our nimble and efficient execution, ensures that we are a reliable partner to several top pharmaceutical firms. Our qualified and competent team is committed to providing prompt and effective service to our customers on a consistent basis.

Facility

Warehouse – 1 and 2

Production Blocks – 6

Quality Control – Wet Analysis and Instrumentation

Quality Assurance

Engineering & Utilities

Human Resources

Effluent Treatment Plant

Solvent Recovery System

State GMP Accredited Facility

Total Capacity: ~325 KL (additional 600 KL planned)

4 Clean Rooms with capacities ranging from 0.25 KL and 3 KL

GLRs and SSRs with capacities ranging from 0.25 KL and 10 KL

Dedicated Pilot Block with Small Reactor Capacities ranging from 0.25 KL to 2.0 KL

Temperature Range from -120°C to +250°C

State-of-the-Art Solvent Recovery System (SRS) with capacity 2200 KL per month

Production Units

The manufacturing facility consists of six production blocks. Stainless steel and glass-lined reactors, each with a distinct capacity and capability, are available in each block. The utilities are planned not only for current manufacturing blocks but also for future expansion. 

  1. 1
    Production block 1

    Reactor area for Intermediate processing. Clean rooms for API Crystallization and Powder processing.

  2. 2
    Production block 2

    Reactor area for intermediate processing.

  3. 3
    Production block 3

    Reactor area for intermediate processing.

  4. 4
    Production block 4

    Reactor area for intermediate processing.

  5. 5
    Production block 5

    Reactor area for intermediate processing.

  6. 6
    Production Block 6

    Reactor area for Intermediate processing. Clean rooms for API Crystallization and Powder processing.

Equipments

Using state-of-the-art machinery, we provide capacities ranging from 10L to 10KL.

SS Reactors

GL Reactors

Centrifuges

Dryers (TDs, VTDs & RCVDs)

Sifter

Blender

Multi Mill

Pulverizers

Agitated Nutsche Filter Dryer (ANFD)

Core Reaction Capabilities

We have expertise managing difficult chemical reactions, such as handling Bu-Li, Li-HMDS, Dibal, bromination, and nitration ones.

Acylation reactions

 Alkylation reactions

 Condensation reactions

Chiral Separations

Coupling Reactions

Hydrogenation without pressure

 Nitration

High Vacuum Distillation

Methylation

Expertise in Chiral Synthesis

Cyanide Reactions

Chlorination

Bromination

Reactions at High Temperature Range up to +250°C

Oxidation

Reduction

Enzymatic Reactions

Silylation

Pressure Capacity upto 20 kg/cm2

Hofmann Rearrangement

 Ketalization

Organolithium Reactions

Grignard Reaction

Oximation

Hydrogenation Under Pressure

Hydrolysis

Privacy Policy

Each customer project executed at Aparna Pharmaceuticals is unique and treated with the utmost confidentiality. Each project that is accomplished is firewalled and coded to protect the customer’s specific confidential information. The underlying values which we bring to any customer relationship are transparency and trust.