Chemical structure:
IUPAC name:
3,5-dimethyltricyclo[3.3.1.13,7]decan-1amine or 3,5-dimethyladamantan-1-amine
CAS number:
19982-08-2
Therapy area:
Anti-depressant
References:
IP/USP
Status:
Commercial scale
Mechanism of action
Memantine is a clinically effective medication for a variety of neurological conditions, including Alzheimer’s disease. Memantine’s main mode of action is thought to include blocking current flow via channels of N-methyl-d-aspartate (NMDA) receptors, a glutamate receptor subfamily with widespread involvement in brain function. Curiously, certain NMDA receptor channel blockers, like ketamine, have severe negative consequences. Memantine’s extraordinary therapeutic efficacy is most likely a combination of its unique properties and inhibitory mechanisms that it shares with ketamine.
DISCLAIMER: PRODUCTS COVERED BY VALID & UNEXPIRED PATENTS ARE NOT OFFERED (OR) SUPPLIED FOR COMMERCIAL SCALE. THE PATENT POSITION SHOULD BE VERIFIED & LIABILITY LIES WITH THE CUSTOMER ONLY. PRODUCTS COVERED BY PATENTS ARE AVAILABLE ONLY FOR R&D USE.