Chemical structure:

IUPAC name:

5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-Pyrrole-3-methanamine (2E)-2-butenedioate (1:1)

CAS number:

881681-00-1

Therapy area:

Anti-ulcer

References:

IH

Status:

Under pilot trials

Mechanism of action

By competitively inhibiting the binding of potassium ions to H+, K+-ATPase (also known as the proton pump), vonoprazan fumarate inhibits the last stage of gastric acid production in gastric parietal cells, an unique mode of action for the drug.

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